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HerbalGram 122 includes articles on a modern state-federal framework for a regulated US cannabis industry; the ethnopharmacologic search for psychoactive drugs; BCM-95 (Curcugreen) Turmeric/Curcumin monograph; Grape Seed Extract Laroratory Guidance Document; kratom research; quince for gastroesophageal reflux during pregnancy; fig and flixweed for IBS with constipation; Permixon saw palmetto extract for lower urinary tract; saffron for depression; tongkat ali (Eurycoma longifolia) profile; and more.